Q&A: METASTATIC BREAST CANCER

Ms Annabel Crabb is one of Australia’s most beloved journalists. She is a multi-faceted writer
and broadcaster who ranges between federal politics, gender, current affairs, history and
cooking and is a sought-after speaker and presenter for her incisive and humorous
approach.

She is the creator and presenter of Ms Represented, and of the long-running political
interview series Kitchen Cabinet, a seventh season of which will air in 2023. She wrote and
presented the ground-breaking documentary series on life inside Australia’s Parliament
House, The House With Annabel Crabb. She also hosts ABC’s popular Australian history and
food series, Back In Time For Dinner. Annabel is a regular face on ABC TV’s election night
and Budget broadcasts and has a long history of appearances on ABC’s Insiders program,
including a stint as acting host in 2019.

She is a regular commentator across the ABC’s radio network. With friend and ABC
colleague Leigh Sales, Annabel hosts the podcast Chat 10 Looks 3, an independent podcast
in which the pair discusses books, film, culture, and cooking. Their first book together, Well Hello, was published in September 2021. Annabel won a Walkley Award for her
biographical work “Stop At Nothing: The Life And Adventures Of Malcolm Turnbull” and
has written several books including 2014 bestseller The Wife Drought.

Annabel boasts the awkward distinction of being Twitter’s most-followed Australian
journalist, with an audience of over half a million.

Associate Professor Lisa Beatty is a Clinical Psychologist with over 15 years of research and clinical expertise in the field of psycho-oncology – the scientific exploration of the psychological impact and treatment of cancer.

Within this field, Lisa is an expert in digital mental health interventions for cancer survivors, a strategy that aims to deliver evidence-based psychological treatments online to those who may not be able to access them otherwise due to distance, fear or distress.

Lisa works at the interface of oncology and psychology and effectively engages with researchers, clinicians, and consumers in both these fields.

Professor Sarah-Jane Dawson is a clinician-scientist. She obtained her medical degree from the University of Melbourne in 1998, and trained as a medical oncologist in Melbourne, Australia.

She completed her PhD at the University of Cambridge, UK. Following postdoctoral studies at the Cancer Research UK Cambridge Institute, she returned to Melbourne in 2014 to head the Molecular Biomarkers and Translational Genomics Laboratory at the Peter MacCallum Cancer Centre.

Her current research interests are focused on the development of noninvasive blood-based biomarkers (‘liquid biopsies’) for clinical application, including early detection, risk stratification and disease monitoring in cancer management.

Dr Shom Goel is a clinician-scientist at the University of Melbourne and the Peter MacCallum Cancer Centre. His research group is focused on understanding the mechanisms underlying response and resistance to contemporary therapies for breast cancer. The team has particular strengths in the study of cell cycle inhibitors and their broad impacts on breast cancer biology.

His research focuses on biological mechanisms underlying activity of, and resistance to, pharmacologic inhibitors of the cell cycle machinery – specifically cyclin-dependent kinases 4 and 6 (CDK4/6). He published the first study demonstrating how CDK4/6 inhibitors can rewire kinase circuitry within cancer cells, and another landmark paper describing how these agents modulate anti-tumour immune responses.